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. 2020 Dec 14;6:14. doi: 10.1038/s41514-020-00053-4

Fig. 1. Progression of hearing impairment in the WT C57BL/6 mice during aging.

Fig. 1

ABR thresholds (a), ABR wave I latencies (b), and ABR wave I amplitudes (c) of the wild-type (WT) C57BL/6 mice at the age of 2, 5, and 12 months (n = 6 for 2-month-old mice, n = 3 for 5-month-old mice, and n = 6 for 12-month-old mice). The data represent the mean ± SEM. *P < 0.05, **P < 0.01. Two-way analysis of variance (ANOVA) followed by Tukey’s multiple comparison test was applied. As the ABR wave I latencies and amplitudes that were induced by a stimulus intensity of 100 dB SPL were measured, one and two 12-month-old mice that exhibited ABR thresholds above 100 dB SPL at 4 and 32 kHz, respectively, were omitted from the waveform analysis shown in b and c.