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. 2020 Dec 11;23(1):140–148. doi: 10.1016/j.neo.2020.11.010

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© 2020 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig. 3 — (A) Karyogram of the U-RT1 cell line. The cell line displays a pseudo-triploid set of chromosomes with recurring abnormalities in chromosomes 1, 10, 19, and 20. (B) Overview of chromosomal aberrations in U-RT1 detected by aCGH. Green marking indicates loss of genetic material in the labelled region, red areas harbour a gain of genetic material in the corresponding chromosomal segment. Aberrations were determined using the ADM-2 algorithm of the Agilent Genomic Workbench. Arrows indicate the location of TP53 (17p13.1), CDKN2A (9p21.3), and NOTCH1 (9q34.3). CLL, chronic lymphocytic leukemia.