Fig. 2.

Applying the 12-gene genomic instability signature for prediction of disease-free and overall survival in independent datasets using Kaplan-Meier analyses. The curves in red reflect carcinoma patients harboring the genomically stable signature, the curves in green represent patients with the one implying genomic instability. For all three examples, statistically significant association of genomic instability with shorter disease-free and overall survival was observed. Figure adapted from Habermann et al. (2011a, b)