Table 3.
Summary of Molecular Subtypes
Molecular Subtypes | Features | Clinical Outcome | Therapeutic Response |
---|---|---|---|
Classical | High expression of epithelial and adhesion-related genes | Best prognosis | Gemcitabine-resistant; Erlotinib-sensitive |
Quasi-Mesenchymal | High expression of mesenchyme-related genes | Worst prognosis | Gemcitabine-sensitive; Erlotinib-resistant |
Exocrine-like | High expression of tumour cell-derived and genes-linked to digestive enzyme | Intermediate prognosis | Not reported |
Note: Data from Collisson et al. 67