Figure 2. Annual Prevalence of Exposure to Clinical Pharmacogenetics Implementation Consortium (CPIC) Level A Medications, Stratified by Drug Class and Individual Analgesics .

A, The annual prevalence of exposure for each drug or drug class was estimated from the model and is plotted on a log axis. If a drug class only had a single included drug, that drug was listed instead of the drug class. For example, ondansetron is listed instead of antiemetic medications. B, Annual prevalence of exposure for analgesics is plotted on a linear scale. The estimated prevalence of exposure for all analgesics was taken from the drug class model in part A, whereas those for oxycodone, codeine, and tramadol were taken from the individual drug models. The whiskers indicate 95% CIs. Non-CPIC level A analgesics were not included. SSRI indicates selective serotonin reuptake inhibitor; TCA, tricyclic antidepressant.