Table 1. . Memory immune cell subsets.
| Subset name | Location | Blood trafficking | Lymph node trafficking | Function |
|---|---|---|---|---|
| Tcm | Lymphoid organs | Yes | Yes | Enhance likelihood of specific T cell–APC encounters and magnitude of the secondary immune response |
| Tem | Nonlymphoid organs | Yes | No | Effector function in chronic and secondary reinfection |
| Trm | Nonlymphoid organs | No | No | Direct tissue immune response and immune surveillance |
| Bm | Germinal center lymphoid organs | Yes | Yes | Secondary humoral immune response |
This table summarizes the main subsets of immune memory cells with their localization and functions.
APC: Antigen-presenting cell; Bm: Memory B lymphocyte; Tcm: Central memory T cell; Tem: Effector memory T cell; Trm: Tissue-resident memory T cell.