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. 2020 Dec 8;15(11):755–761. doi: 10.2217/fvl-2020-0132

Table 1. . Memory immune cell subsets.

Subset name Location Blood trafficking Lymph node trafficking Function
Tcm Lymphoid organs Yes Yes Enhance likelihood of specific T cell–APC encounters and magnitude of the secondary immune response
Tem Nonlymphoid organs Yes No Effector function in chronic and secondary reinfection
Trm Nonlymphoid organs No No Direct tissue immune response and immune surveillance
Bm Germinal center lymphoid organs Yes Yes Secondary humoral immune response

This table summarizes the main subsets of immune memory cells with their localization and functions.

APC: Antigen-presenting cell; Bm: Memory B lymphocyte; Tcm: Central memory T cell; Tem: Effector memory T cell; Trm: Tissue-resident memory T cell.