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. 2020 Nov 18;3(6):1100–1110. doi: 10.1021/acsptsci.0c00073

Figure 2.

Figure 2

AD16 Reduces Microglial Area in the Brain of APP/PS1 Mice. Nine-month-old male APP/PS1 mice were either orally dosed with vehicle or AD16 for 3 months. Representative immunostaining of Iba-1 in the hippocampus of APP/PS1 group (A) and AD16 treated group (B). Quantification of the area of Iba-1 positive microglia in the brain of AD mice (n = 5 per group) receiving AD16 or vehicle (C). Scale bar: 200 μm. Statistical comparisons were performed by unpaired Student’s t test. Data are presented as means ± SD; ***p < 0.001.