Efficacy of the NPB and cisplatin combination treatment in ovarian
cancer xenografts. Representative images (A) and quantification (B–D)
of immunohistochemistry analyses of positive cell (%) in the tumor
tissues for selected markers, pBAD (Ser99), Ki67, and TUNEL. Results
were statistically analyzed with one-way ANOVA followed by Dunnett’s
test post hoc. (Cycle 1) I̵/&P < 0.05, I̵ I̵ /&&P < 0.01 and I̵ I̵ I̵/&&&P < 0.001, compared with the combination-treated
group; *P < 0.05, **P < 0.01
and ***P < 0.001, compared with the vehicle-treated
group. Cycle 2: #P < 0.05, ##P < 0.01 and ###P < 0.001, compared with the combination-treated group.