Figure 4.

In each of the 4 stains on the left, the rectangles are the region of interest identified by the convolutional neural net model. Yellow circles represent the manually annotated glomeruli. By strengthening strong and reducing weak signals from the individual stains, a final composite region of interest is created as displayed on the H and E stained slide on the right. Note that this process reduces the size of the region of interests that encompass annotated glomeruli, indicating a more precise localization of glomeruli