Table 2.

The role of basophils and eosinophils in nematode infections.

Helminth	The role of Basophils	The role of eosinophils	Reference
Nippostrongylus brasiliensis	- Basophils protect from re-infection in the skin.	- CXCR6+ST2+ mTh2 cells facilitate eosinophilia in the lungs to reduce the fecundity in the lungs in re-infection.	(73)
			(77)
Strongyloides venezuelensis	- Basophil-depletion in Mcpt8DTR mice revealed small contribution of basophils in primary infection and minor or no roles in secondary infection.	- The duration of Sv was increased in ΔdblGATA mice in primary infection (unpublished data)	(75)
			(74)
Strongyloides ratti	- The number of intestinal nematodes and fecal eggs is elevated in Mcpt8-Cre mice.	- IL-5 deficiency increased the number of intestinal worms and fecal eggs.	(76)
			(78)
Heligmosomoides polygyrus	- Mcpt8-Cre mice have a high number of eggs in feces during re-infection.	- The fecundity of Hp was increased in ΔdblGATA and PHIL mice during re-infection.	(48)
			(79)
Trichinella spiralis	- Th2 immune response is reduced in Bas-TRECK mice.	- Eosinophils increased the survival of muscle larvae	(33)
			(80)
Trichuris muris	- Basophil depletion via MAR-1 treatment increases the number of Th2 cells and impairs Tm expulsion.	- Eosinophil depletion by anti-IL-5 Ab treatment does not change worm expulsion.	(54)
			(81)