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. 2020 Dec 15;6(12):e05684. doi: 10.1016/j.heliyon.2020.e05684

Table 2.

Results of the meta-analysis of the sex, age, comorbidity and clinical manifestation.

Overall Parameter Individual Parameter OR or RR 95% CI p value I2
Sex Sex 2.41 1.93–3.02 <0.00001 67%
Age Age≥50 vs. age<50 3.36 1.79–6.30 0.0002 89%
Age≥65 vs. age<65 0.79 0.59–1.06 0.11 88%
Comorbidity Any comorbidity 3.13 2.26–4.32 <0.00001 64%
Hypertension 2.35 1.83–3.02 <0.00001 66%
Diabetes 2.42 1.84–3.19 <0.00001 58%
Cerebrovascular disease 3.78 2.22–6.43 <0.00001 35%
Cardiovascular disease 3.33 2.47–4.47 <0.00001 47%
Respiratory disease 2.58 1.76–3.77 <0.00001 33%
Malignancy 2.32 1.63–3.32 <0.00001 9%
Chronic kidney disease 2.27 1.41–3.65 0.0007 32%
Chronic liver disease 1.70 1.19–2.42 0.003 0%
Overall 2.59 2.31–2.89 <0.00001 49%
Symptoms Fever 1.68 1.29–2.19 0.0001 54%
Cough 1.41 1.11–1.77 0.004 63%
Fatigue 1.26 1.03–1.55 0.03 36%
Anorexia 2.38 1.60–3.54 <0.0001 0%
Myalgia 1.30 0.98–1.71 0.07 58%
Dyspnea 4.30 2.98–6.22 <0.00001 79%
Chest tightness 2.11 1.30–3.42 0.002 72%
Sputum production 1.35 1.00–1.82 0.05 55%
Hemoptysis 4.93 2.43–10.02 <0.0001 0%
Pharyngalgia 0.91 0.30–2.74 0.87 69%
Diarrhea 1.35 1.03–1.78 0.03 30%
Nausea 1.26 0.48–3.31 0.64 86%
Vomiting 1.48 0.97–2.25 0.07 24%
Abdominal pain 2.38 1.25–4.52 0.008 0%
Headache 1.19 0.83–1.72 0.34 48%
Dizziness 1.40 0.87–2.28 0.17 22%
Sore throat 1.60 0.88–2.91 0.12 66%
Overall 1.62 1.46–1.79 <0.00001 68%

Risk Ratio (RR) was used only for age.