Table 1. Report of rheumatoid arthritis successfully treated with biologics.
References | Number of cases | Biologics | First biopsy organ | First biopsy organ lesions | Repeat biopsy organ | Repeat biopsy organ lesions | Number of kidney function improvement or stable cases |
---|---|---|---|---|---|---|---|
[8] | 4 | Infliximab | Gastrointestinal mucosa | Congo-red-positive deposits were seen in gastric mucosal and submucosal lesions | Gastrointestinal mucosa | The percentage of areas of amyloid deposition was decreased | 4 |
[8] | 10 | Etanercept | Gastrointestinal mucosa | Congo-red-positive deposits were seen in gastric mucosal and submucosal lesions | Gastrointestinal mucosa | The percentage of areas of amyloid deposition was decreased | 7 |
[9] | 1 | Etanercept | Gastrointestinal mucosa | Heavy deposition of amyloid was visible in lamina propria and vascular walls of all specimens | Gastrointestinal mucosa | Amyloid deposition was decreased | 1 |
[10] | 1 | Tocilizumab | Kidney | Deposition of amyloid was seen in the mesangial area and vascular wall | n/a | n/a | 1 |
[12] | 3 | Tocilizumab | Salivary gland | Deposition of amyloid was seen | n/a | n/a | 2 |
[12] | 5 | Tocilizumab | Kidney | Deposition of amyloid was seen | n/a | n/a | 5 |
n/a = not available.