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. 2020 Nov 6;95(1):54–61. doi: 10.5414/CN109971

Table 1. Report of rheumatoid arthritis successfully treated with biologics.

References Number of cases Biologics First biopsy organ First biopsy organ lesions Repeat biopsy organ Repeat biopsy organ lesions Number of kidney function improvement or stable cases
[8] 4 Infliximab Gastrointestinal mucosa Congo-red-positive deposits were seen in gastric mucosal and submucosal lesions Gastrointestinal mucosa The percentage of areas of amyloid deposition was decreased 4
[8] 10 Etanercept Gastrointestinal mucosa Congo-red-positive deposits were seen in gastric mucosal and submucosal lesions Gastrointestinal mucosa The percentage of areas of amyloid deposition was decreased 7
[9] 1 Etanercept Gastrointestinal mucosa Heavy deposition of amyloid was visible in lamina propria and vascular walls of all specimens Gastrointestinal mucosa Amyloid deposition was decreased 1
[10] 1 Tocilizumab Kidney Deposition of amyloid was seen in the mesangial area and vascular wall n/a n/a 1
[12] 3 Tocilizumab Salivary gland Deposition of amyloid was seen n/a n/a 2
[12] 5 Tocilizumab Kidney Deposition of amyloid was seen n/a n/a 5

n/a = not available.