Table 1.
Proposed Diagnostic criteria for Long COVID-19 |
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A. ESSENTIAL CRITERIA (Evidence of preceding infection with SARS-CoV-2 within last 2–4 weeks) |
Symptomatic |
Confirmed |
Clinical features consistent with COVID-19, with positive throat swab RT-PCR |
Clinical features consistent with COVID-19, with negative throat swab RT- PCR, with positive antibody testing |
Probable |
Clinical features consistent with COVID-19, with negative throat swab RT-PCR and antibody testing, with CT thorax or chest X ray consistent with COVID-19 in presence of contact with confirmed or suspected case of COVID-19 within 2 weeks of onset of symptoms |
Clinical features consistent with COVID-19, with negative throat swab RT-PCR, antibody testing and negative CT thorax and chest X ray in presence of contact with confirmed or suspected case of COVID-19 within 2 weeks of onset of symptoms |
Possible |
Clinical features consistent with COVID-19, with negative throat swab RT-PCR and antibody testing, with CT thorax or chest X ray consistent with COVID-19 in the absence of contact with confirmed or suspected case of COVID-19 within 2 weeks of onset of symptoms, in the setting of community transmission |
Clinical features consistent with COVID-19, with negative throat swab RT-PCR, antibody testing and negative CT thorax and chest X ray in the absence of contact with confirmed or suspected case of COVID-19 within 2 weeks of onset of symptoms, in the setting of community transmission |
Doubtful |
Clinical features consistent with COVID-19, with negative throat swab RT-PCR, antibody testing and negative CT thorax and chest X ray in the absence of contact with confirmed or suspected case of COVID-19 within 2 weeks of onset of symptoms in the absence of community transmission |
Asymptomatic |
Confirmed |
Either positive throat swab RT-PCR or positive antibody testing or both |
Probable |
Negative throat swab RT-PCR and antibody testing with CT thorax, chest X ray consistent with COVID-19 in presence of contact with confirmed or suspected case of COVID-19 |
Possible |
Negative throat swab RT-PCR, antibody testing and negative CT thorax and chest X ray in presence of contact with confirmed or suspected case of COVID-19 |
Doubtful |
Negative throat swab RT-PCR, antibody testing and negative CT thorax and chest X ray in the absence of contact with confirmed or suspected case of COVID-19 in the setting of community transmission |
B.CLINICAL CRITERIA Symptoms of Long COVID-19 |
Presence of symptoms (new or persistent) like fatigue, breathlessness, cough, joint pain, chest pain, muscle aches, headache and so on which could not be attributed to any other cause |
C.DURATION CRITERIA Duration |
In SARS-CoV-2 infected symptomatic individuals, presence of symptoms |
More than 2 weeks in mild disease More than 4 weeks in moderate/severe illness More than 6 weeks in critical illness |
In SARS-CoV-2 infected asymptomatic individuals, presence of symptoms |
Appearance of symptoms after 2 weeks of RT-PCR positivity Appearance of symptoms after 1 weeks of antibody positivity Appearance of symptoms after 2 weeks of positive CT thorax or chest X ray Appearance of symptoms after 2 weeks after contact with suspected or positive case of COVID-19 Anytime in doubtful cases |
(Note: Those who did not undergo throat swab RT-PCR or antibody testing also considered as test negative).