Scheme 3.

Synthesis of target compounds 71–74. Reagents and conditions: (a) hydrazine monohydrate, EtOH, reflux, 3 h; (b) CH(OMe)3, PTSA, 85 °C, 2 h or CH3C(OMe)3, HOAc, m-xylene, reflux, 6 h.

Synthesis of target compounds 71–74. Reagents and conditions: (a) hydrazine monohydrate, EtOH, reflux, 3 h; (b) CH(OMe)3, PTSA, 85 °C, 2 h or CH3C(OMe)3, HOAc, m-xylene, reflux, 6 h.