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. Author manuscript; available in PMC: 2021 Apr 7.
Published in final edited form as: Circ Cardiovasc Qual Outcomes. 2020 Apr 7;13(4):e006127. doi: 10.1161/CIRCOUTCOMES.119.006127

Table 1.

Parameter Probabilities, Sensitivity Analysis Ranges, and Sources

Parameter Probability #/N 95% CI Range Distribution Source
All Years
 Technical success 0.84 120/143 0.77–0.89 0.70–1.0 Beta Primary Data
 Post FAV fetal demise 0.08 12/143 0.04–0.13 0.04–0.30 Beta Primary Data
 No FAV fetal demise 0.06 4/72 0.02–0.12 0.00–0.20 Beta Beroukhim et al.23
 TS: Biv outcome 0.50 56/111 0.41–0.60 0.10–0.70 Beta Primary Data
 TU: Biv outcome 0.16 3/19 0.04–0.35 0.00–0.50 Beta Primary Data
2009–2017
 Technical success 0.94 67/71 0.88–0.98 0.70–1.00 Beta Primary Data
Post FAV fetal demise 0.04 3/71 0.01–0.10 0.01–0.20 Beta Primary Data
 TS: Biv outcome 0.66 42/64 0.54–0.77 0.10–0.70 Beta Primary Data
3-year Outcomes
 Survival
  Post TS FAV: Biv 0.96 0.90–1.0 Beta Primary Data
  SV (MS/AS) 0.77 0.64–0.86 Beta SVR18
 Postnatal LE (months)
  Post TS FAV: BiV 35.4 34.2–36.5 Normal Primary Data
  SV (MS/AS) 31.0 28.3–33.7 Normal SVR18
6-year Outcomes
 Survival
  Post TS FAV: Biv 0.92 0.83–1.0 Beta Primary Data
  SV (MS/AS) 0.72 0.58–0.82 Beta SVR19
 Postnatal LE (months)
  Post TS FAV: Biv 69.4 66.2–72.5 Normal Primary Data
  SV (MS/AS) 57.0 52.6–64.7 Normal SVR19

Biv = biventricular circulation; FAV = fetal aortic valvuloplasty; MS/AS = mitral stenosis/aortic stenosis; SVR = Single Ventricle Reconstruction trial secondary analysis; TS = technically successful; TU = technically unsuccessful