Table 1.
The characteristics of the included RCTs.
| Cases |
Sex male/female | Age(years) mean | Disease course, range, mean | Diagnostic criteria | Reference | ||
|---|---|---|---|---|---|---|---|
| No | T | C | |||||
| 1 | 30 | 30 | 24/36 | 52.8 | 2.1y | ACR 1997 | Yu et al. (2017) |
| 2 | 40 | 40 | T:35/5 C:36/4 | T:45.1 C:44.8 | T:2.8y C:2.7 y | NA | Wang (2015) |
| 3 | 30 | 30 | T:28/2 C:29/1 | T:44.1 C:41.8 | T:2.9y C:3.2y | ACR 1997 | He et al. (2013) |
| 4 | 35 | 35 | T:29/6 C:30/5 | T:46.5 C:47.2 | T:2d-20y C:3d-21y | ACR 1997 | Shen et al. (2014) |
| 5 | 45 | 45 | T:34/11 C:31/14 | T:46.36 C:45.78 | T:3d-12y C:7d-16y | ACR 1997 | He (2015) |
| 6 | 34 | 34 | T:16/18 C:20/14 | T:54.5 C:56.1 | T:2.1y C:2.5y | NA | Luo (2017) |
| 7 | 74 | 74 | T:59/15 C:57/17 | T:56.7 C:55.5 | T:11.5y C:11.5y | ACR 1997 | Li et al. (2018) |
| 8 | 30 | 30 | T:19/11 C:17/13 | T:44.2 C:43.5 | T:0.67y-3y C:1y-3y | NA | Xie and Chen (2018) |
| 9 | 46 | 46 | T:29/17 C:30/16 | T:43.9 C:42.6 | T:43.6m C:47.9m | EULAR 2011 | Chen (2018) |
| 10 | 40 | 40 | T:32/8 C:34/6 | T:44.5 C:44.8 | T:47.8m C:48.4m | ACR 1997 | Hu and Luo (2013) |
| 11 | 45 | 38 | T:44/1 C:36/2 | T:46.3 C:47.8 | T:1d-22y C:2d-18y | ACR 1997 | Xu and Chen (1998) |
| 12 | 45 | 45 | T:39/6 C:40/5 | T:45.65 C:45.7 | NA | ACR 1997 | Zhu (2019) |
| 13 | 43 | 43 | T:39/4 C:41/2 | T:40.07 C:39.22 | T:4.5y C:4.78y | ACR 1997 | Qiao (2019) |
T: trail group; C: control group; d: day; m: month; y: year; ACR: American college of rheumatology; EULAR: European league against rheumatism; NA: not available.