FIG 12.

Alignment of the CHIKV nsP3 HVD fragment that contains the FHL1-binding site. The amino acid sequences of the FHL1-binding fragment of CHIKV sequences were downloaded from GenBank and aligned using Jalview 2.11.10. The redundant sequences were deleted. The black line indicates the predicted FHL1-binding site. The blue lines indicate the amino acid sequences with the highest levels of identity. The red line indicates the second binding site of CD2AP. The black arrows point to F429 and F430.