Fig 5. Comparison of signal-to-noise ratio for oligonucleotide detection using Eprobe.

The signal values of each method were detected in the absence/presence of target oligonucleotide in 100 pM Eprobe solution. (A) Oligonucleotide detection by conventional method. Count rates in the absence and presence of target oligonucleotide are 1.2 kHz and 9.1 kHz, respectively. (B) Oligonucleotide detection by SSMC. Numbers of peaks in the absence and presence of target oligonucleotide is 2 and 4652, respectively.