Table 2.
Baseline characteristics, laboratory and echocardiography results of all patients according to median copeptin levels.
| Copeptin level >69.13 pmol/L (n = 60) | Copeptin level <69.13 pmol/L (n = 62) | P value | |
| Age, yrs | 58.5 ± 11.6 | 56.8 ± 9.8 | .534∗ |
| Female gender, n(%) | 20 (33.3) | 12 (19.4) | .171† |
| Hypertension, n(%) | 12 (20) | 14 (22.6) | .527† |
| Diabetes mellitus, n(%) | 12 (20) | 16(25.8) | .408† |
| Hyperlipidemia, n(%) | 16 (26.7) | 18 (29) | .532† |
| Smoking, n(%) | 50 (83.3) | 50 (80.6) | .524† |
| Anterior MI, n(%) | 26 (43.3) | 30 (48.4) | .445† |
| Systolic blood pressure, mmHg | 120 (110–126) | 120 (110–130) | .137‡ |
| Diastolic blood pressure, mmHg | 77.5 (70–80) | 80 (70–85) | .449‡ |
| Heart rate, beat/min | 87.5 (80–90) | 82 (80–90) | .142‡ |
| Echocardiography parameters | |||
| LVEDD, mm | 49.5 (47–52) | 47 (45–50) | .007‡ |
| LVESD, mm | 28.2 (25.9–31.4) | 25.3 (24.7–27.5) | .006‡ |
| LVEF, % | 41 (35–48) | 45 (45–46) | .053‡ |
| E (m/s) | 0.7 (0.6–0.9) | 0.7 (0.5–0.8) | .290‡ |
| A (m/s) | 0.65 (0.53–0.71) | 0.60 (0.5–0.7) | .145‡ |
| E/A | 1.16 (0.85–1.5) | 1.25 (0.83–1.44) | .862‡ |
| E’m peak velocity (cm/s) | 7.1 (5.6–8.1) | 8.1 (6.3–9.4) | .036‡ |
| A’m peak velocity (cm/s) | 9 (6.7–11) | 10.2 (8.7–12) | .060‡ |
| S m peak velocity (cm/s) | 6.7 (5.5–7.4) | 7 (6–8) | .051‡ |
| E/E’m | 10.2 (8.4–13.2) | 8.6 (7.1–11.1) | .014‡ |
| Laboratory parameters | |||
| Hemoglobin, g/dL | 14.3 (13–15.3) | 15.4 (14.4–16) | .006‡ |
| WBC, cells/mL | 10.55 (8.6–11.9) | 10.5 (8.8–13.2) | .681‡ |
| Platelet count, cells/mL | 256 (207–299) | 231 (182–266) | .071‡ |
| Fasting glucose, mg/dl | 92.5 (86.7–98.5) | 90 (87–97) | .238‡ |
| Creatinine, mg /dl | 1.05 (0.85–1.2) | 0.94 (0.83–1.07) | .220‡ |
| AST, U/L | 127 (43.7–205) | 72 (31–187) | .226‡ |
| Troponin I, ng /dL | 0.05 (0.01–18.3) | 0.18 (0.01–6.2) | .811‡ |
| CK-MB, ng /dL | 36.5 (18.5–128) | 64 (19–201) | .302‡ |
| Total cholesterol, mg/dL | 178.5 (151.7–217) | 183 (149–208) | .834‡ |
| LDL cholesterol, mg /dL | 136.5 (116.7–159) | 142 (117–156) | .874‡ |
| HDL cholesterol, mg /dL | 41.5 (35–47.5) | 38 (36–42) | .138‡ |
| Triglyceride, mg/dL | 137 (73.5–177) | 117 (106–175) | .579‡ |
| Copeptin, pmol/l | 156.1 (115–223) | 40.5 (16.4–57) | <.001‡ |
Continuous variables are presented mean ± standard deviation or median. Nominal variables are presented with frequency and percentage.
A’m = late diastolic myocardial peak velocity of mitral lateral annulus, A = late diastolic peak velocity, AST = aspartate aminotransferase, CK-MB = creatinine kinase myocardial band, E’m = early diastolic myocardial peak velocity of mitral lateral annulus, E = early diastolic peak velocity, EF = Ejection fraction, EF = Ejection fraction, HDL = CK-MB = creatinine kinase myocardial band, HDL = High-density lipoprotein, LDL = Low-density lipoprotein, LV = Left ventricle, LVEDD = Left ventricle end-diastolic diameter, LVESD = Left ventricle end-systolic diameter, S m = peak systolic velocity of mitral lateral annulus, WBC = White blood cell.
Student T test.
Pearson Chi-square.
Mann–Whitney U test.