Fig 1. mIFN-α expression driven by mDEF201 in vivo.

5-day-old BALB/c mice were administered intranasally with 5 x 10⁶ PFU of mDEF201 or Ad5, and serum mIFN-α concentration was measured at different time points by ELISA. Values presented as mean and individual values from 3 to 4 mice. P values were determined using the Student's t-test. *P < 0.05; **P < 0.01; ***P < 0.001.