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. 2020 Dec 8:1–21. doi: 10.1080/07391102.2020.1852117

Table 8.

Bioactivity scores of N. sativa phytoconstituents versus standard drugs hydroxychloroquine and ivermectin.

  Parameters of bioactivity score (BAS)
S. No. Phytocomponents GPCR Ligand Ion Channel Modulator Kinase Inhibitor Nuclear Receptor Ligand Protease Inhibitor Enzyme Inhibitor
1. 24-Methylene-Cycloartanol 0.14 0.11 −0.37 0.90 0.06 0.60
2. Alpha-Spinasterol 0.18 0.05 −0.30 0.68 0.06 0.53
3. Beta-Amyrin 0.22 −0.05 −0.31 0.67 0.11 0.56
4. Beta-Sitosterol 0.14 0.04 −0.50 0.73 0.07 0.51
5. Campesterol 0.11 0.01 −0.48 0.71 0.01 0.50
6. Citrostadienol 0.15 0.15 −0.34 0.89 0.13 0.66
7. Cycloartenol 0.21 0.10 −0.40 0.86 0.14 0.66
8. Cycloeucalenol 0.14 0.14 −0.37 0.92 0.10 0.61
9. Taraxerol 0.21 0.02 −0.20 0.54 0.00 0.49
10. Tirucallol 0.18 −0.05 −0.39 0.82 0.06 0.64
11. Hydroxychloroquine 0.35 0.30 0.44 −0.12 0.12 0.15
12. Ivermectin −2.49 −2.86 −3.23 −2.94 −1.89 −2.53