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. Author manuscript; available in PMC: 2021 Dec 1.
Published in final edited form as: Circ Heart Fail. 2020 Nov 24;13(12):e007508. doi: 10.1161/CIRCHEARTFAILURE.120.007508

Table 2.

Rates and relative risks of heart failure according to categories of time-varying SB.

Total Sedentary Behavior (hr/d) Trend
≤6.5 6.6–9.5 >9.5 P-value
Total SB (hr/d) median 5.0 8.0 12.0
Cases 470 426 506
Crude rate* 1.9 2.2 2.4
Model 1, HR (95% CI) 1.00 (ref) 1.15 (1.01, 1.31) 1.42 (1.25, 1.61) <.001
Model 2, HR (95% CI) 1.00 (ref) 1.11 (0.97, 1.27) 1.29 (1.14, 1.47) <.001
Model 3, HR (95% CI) 1.00 (ref) 1.11 (0.97, 1.26) 1.27 (1.11, 1.44) <.001
Model 4, HR (95% CI) 1.00 (ref) 1.10 (0.96, 1.25) 1.24 (1.09, 1.41) <.001
Sitting Time (hr/d)
≤4.5 4.6–8.5 >8.5
Sitting time (hr/d) median 4.5 6.5 10.5
Cases 488 595 319
Crude rate* 1.9 2.3 2.4
Model 1, HR (95% CI) 1.00 (ref) 1.14 (1.01, 1.28) 1.54 (1.34, 1.78) <.001
Model 2, HR (95% CI) 1.00 (ref) 1.09 (0.97, 1.23) 1.39 (1.20, 1.60) <.001
Model 3, HR (95% CI) 1.00 (ref) 1.09 (0.97, 1.23) 1.37 (1.19, 1.58) <.001
Model 4, HR (95% CI) 1.00 (ref) 1.08 (0.95, 1.21) 1.33 (1.15, 1.54) <.001

HR, hazard ratio; CI, confidence interval.

*

Crude rate, HF cases per 1,000 person years.

Model 1 includes age (years), race-ethnicity (6 categories), education (3 categories), income (4 categories) smoking (never, past, current), alcohol consumption (never, past, current), hormone therapy use (never, past, current), history of hysterectomy.

Model 2 includes above factors and BMI (kg/m2), systolic and diastolic BP (mmHg), physical function score (continuous), history of treated diabetes and hypertension, and history of atrial fibrillation.

Model 3 includes above factors and time-varying CHD (myocardial infarction, coronary revascularization procedures).

Model 4 includes above factors and self-reported baseline total recreational physical activity (MET-hr/wk).