Figure 7.

Genetic map of the miniature inverted-repeated transposable element (MITE)-integron complex present among 15 of the 21 plasmids. The insertion site of the MITEs is shown in (A). The structure of each MITE variant is shown in (B) and is grouped according to MITE “type.” The plasmids that carry each MITE variant are listed above/below each genetic map. Plasmid names are colored according to the geographic region from which they were sampled, as described in Figure 3. Directional blocks represent genes, while orange arrows represent MITEs as annotated in the top right corner of the figure. All maps are drawn to scale. To the right of each MITE type is the inferred plasmid core-genome phylogeny, highlighting each plasmid that carries the corresponding MITE type. Note that, the same MITE type often occurred in multiple plasmid lineages and could also be present on plasmids from different geographic regions. This suggests that this MITE-resistance region is highly dynamic and transmissible.