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. 2020 Dec 15;10:21993. doi: 10.1038/s41598-020-78642-2

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Change in serotonin and child psychosocial measurements. (a) Change in fecal serotonin between IG (n = 23) and CG (n = 15), pre- and post-intervention. (b) Change in PSS-C score in child psychosocial measurements between IG (n = 20) and CG (n = 9). (c) Change in score of anger in child psychosocial measurements between IG (n = 24) and CG (n = 12). (d) Change in score of prosocial in child psychosocial measurements between IG (n = 24) and CG (n = 12). (e) Association between serotonin and PSS-C score. (f) Association between serotonin and anger frequency. (g) Association between serotonin and adequate sleep. In (a) to (d) blue colour indicated pre-samples, yellow colour indicated post-samples. In (e), different colour of node and dotted-line indicated different individual, and the black dotted-line indicated the overall association. In (f) and (g), four colour indicated four degrees of anger and adequate sleep frequency.