TABLE 5.

Multivariate Cox regression analyses for identifying independent clinical characteristics related to EC patients’ OS and PFS.

Clinical feature	Multivariate analysis (OS)			Multivariate analysis (PFS)
	HR	95%CI of HR	P value	HR	95%CI of HR	P value
Risk score	2.413	1.324–4.398	0.004	4.120	2.383–7.122	<0.001
Age, y	1.030	1.002–1.052	0.032	0.999	0.978–1.020	0.910
Race
Black	–	–	–	1 (reference)
Other	–	–	–	0.511	0.164–1.590	0.246
White	–	–	–	1.400	0.822–2.559	0.246
AJCC stage
I	1 (reference)			1 (reference)
II-IV	2.572	1.459–4.536	0.001	1.756	1.130–2.729	0.012
Grade
Low	1 (reference)			1 (reference)
High	1.464	0.739–2.900	0.274	0.638	0.367–1.110	0.112
Histologic_type
EEA	1 (reference)			1 (reference)
MSE	1.237	0.426–3.592	0.696	1.318	0.497–3.495	0.579
SEA	0.875	0.485–1.581	0.659	1.193	0.700–2.035	0.516
Margin_status
R0	1 (reference)			1 (reference)
R1/2	1.941	1.035–3.641	0.039	1.691	0.946–3.020	0.076
Surgical_approach
Minimally Invasive	–	–	–	1 (reference)
Open	–	–	–	0.622	0.402–0.963	0.033