Figure 5.

Expression and activity of HPV-related transcription factors in HNSCC. HPV-positive and HPV-negative HNSCC displayed distinguishable transcriptional profiles. Transcription factors broadly classified as inducible (Purple) and constitutively-active (Blue) include: 1. AP1 (Gupta et al., 2015), 2. NF-κB (Fontaine et al., 2000; Bano et al., 2018; Zhang et al., 2018) 3. STAT3 (Gaykalova et al., 2015; Verma et al., 2017), 4. GR/PR (Mohamed et al., 2018; Kost et al., 2019) 5. FOXA1 (Karpathiou et al., 2017; Li et al., 2019) 6. SOX2 (Gut et al., 2018; Dogan et al., 2019) 7. YY1 (Ferris et al., 2005; He et al., 2011). *No specific study in HNSCC. Red text: Data from cervical cancer; Pink text: Data of vulvar carcinoma.