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Heparin decreases the expressions of inflammation-related factors and level of EH4 in vivo. At 6 h before the onset of surgery, blood samples acquired by removing the mice's eyeballs were used to determine the expression levels of H4 (A), TNF-α (B), and IL-6 (C) in in blood serum by ELISA. Data are presented as mean ± SD, n = 3 per group of the representative data from three independent experiments; *P < 0.05.
