Table 1.

Association between hypoxia status and clinicopathological characteristics in breast cancer patients.

characteristic	Total	Cluster1 (199)		Cluster2 (504)		P Value*
		No. of patients	%	No. of patients	%
ER Status
Negative	161	104	52.26	57	11.31	<0.001
Positive	542	95	47.74	447	88.69
PR Status
Negative	227	122	61.31	105	20.83	<0.001
Positive	476	77	38.69	399	79.17
HER2 Status
Negative	597	159	79.90	438	86.90	0.019
Positive	106	40	20.10	66	13.10
PAM50 Subtype
Her2	53	33	16.58	20	3.97	<0.001
Luminal A	336	29	14.57	307	60.91
Luminal B	160	40	20.10	120	23.81
Basal/Normal	137	92	46.23	45	8.93
T Stage
T1-T2	602	171	85.93	431	85.52	0.888
T3-T4	101	28	14.07	73	14.48
N Stage
N0-N1	579	162	81.41	417	82.74	0.677
N2-N3	124	37	18.59	87	17.26
M Stage
M0	648	179	89.95	469	93.06	0.440
M1	13	5	2.51	8	1.59
MX	42	15	7.54	27	5.36
Stage
Stage I-II	532	150	75.38	382	75.79	0.107
Stage III-IV	171	49	24.62	122	24.21

*Chi-square Test.