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. 2020 Oct;224:108–115. doi: 10.1016/j.schres.2020.09.018

Table 3.

Unadjusted and adjusted association between fatty acid measures at age 7 years and psychotic experiences at age 18 years.

Outcome Exposure Unadjusted
Adjusteda
N N (%) with PE
OR (95% CIs) P OR (95% CIs) P
Definite/suspected psychotic experiences versus none LA 0.993 (0.851, 1.159) 0.931 1.001 (0.856, 1.172) 0.986 2310 174 (7.53)
AA 0.853 (0.728, 0.999) 0.049 0.873 (0.742, 1.026) 0.100
AdA 0.826 (0.702, 0.972) 0.021 0.855 (0.723, 1.012) 0.068
OA 0.822 (0.697, 0.970) 0.020 0.842 (0.711, 0.998) 0.048
Total n6 0.938 (0.805, 1.094) 0.415 0.954 (0.817, 1.114) 0.553
ALA 1.043 (0.896, 1.214) 0.586 1.038 (0.891, 1.210) 0.633
EPA 0.997 (0.853, 1.164) 0.967 0.987 (0.843, 1.156) 0.871
DPA 0.982 (0.841, 1.146) 0.813 0.995 (0.848, 1.167) 0.948
DHA 0.978 (0.841, 1.139) 0.776 1.016 (0.871, 1.186) 0.835
Total n3 0.996 (0.855, 1.160) 0.956 1.020 (0.874, 1.191) 0.803
AA:EPA 0.890 (0.758, 1.044) 0.152 0.912 (0.777, 1.072) 0.265
n6:n3 0.968 (0.828, 1.132) 0.688 0.956 (0.813, 1.124) 0.585

Note: OR, odds ratio per standard deviation increase in fatty acid level; 95% CI, 95% confidence interval; P, p-value for association between fatty acid levels at age 7 years and psychotic experiences at age 18 years; LA, linoleic acid (18:2n-6); AA, arachidonic acid (20:4n-6); AdA, docosatetraenoic acid (trivial name adrenic acid; 22:4n-6); OA, omega-6 docosapentaenoic acid (trivial name osbond acid; 22:5n-6); total n6, total levels of omega-6 fatty acids; ALA, α-linolenic acid (18:3n-3); EPA, eicosapentaenoic acid (20:5n-3); DPA omega-3 docosapentaenoic acid (22:5n-3); DHA docosahexaenoic acid (22:6n-3); total n3, total levels of omega-3 fatty acids; n6:n3, ratio of total levels of omega-6 to total levels of omega-3 fatty acids.

a

Adjusted for gender; ethnic group; highest parental social class; maternal education; birth weight; family adversity index, body mass index at age 7 years; energy intake at age 7 years.