Table 3.
Outcome | Exposure | Unadjusted |
Adjusteda |
N | N (%) with PE | ||
---|---|---|---|---|---|---|---|
OR (95% CIs) | P | OR (95% CIs) | P | ||||
Definite/suspected psychotic experiences versus none | LA | 0.993 (0.851, 1.159) | 0.931 | 1.001 (0.856, 1.172) | 0.986 | 2310 | 174 (7.53) |
AA | 0.853 (0.728, 0.999) | 0.049 | 0.873 (0.742, 1.026) | 0.100 | |||
AdA | 0.826 (0.702, 0.972) | 0.021 | 0.855 (0.723, 1.012) | 0.068 | |||
OA | 0.822 (0.697, 0.970) | 0.020 | 0.842 (0.711, 0.998) | 0.048 | |||
Total n6 | 0.938 (0.805, 1.094) | 0.415 | 0.954 (0.817, 1.114) | 0.553 | |||
ALA | 1.043 (0.896, 1.214) | 0.586 | 1.038 (0.891, 1.210) | 0.633 | |||
EPA | 0.997 (0.853, 1.164) | 0.967 | 0.987 (0.843, 1.156) | 0.871 | |||
DPA | 0.982 (0.841, 1.146) | 0.813 | 0.995 (0.848, 1.167) | 0.948 | |||
DHA | 0.978 (0.841, 1.139) | 0.776 | 1.016 (0.871, 1.186) | 0.835 | |||
Total n3 | 0.996 (0.855, 1.160) | 0.956 | 1.020 (0.874, 1.191) | 0.803 | |||
AA:EPA | 0.890 (0.758, 1.044) | 0.152 | 0.912 (0.777, 1.072) | 0.265 | |||
n6:n3 | 0.968 (0.828, 1.132) | 0.688 | 0.956 (0.813, 1.124) | 0.585 |
Note: OR, odds ratio per standard deviation increase in fatty acid level; 95% CI, 95% confidence interval; P, p-value for association between fatty acid levels at age 7 years and psychotic experiences at age 18 years; LA, linoleic acid (18:2n-6); AA, arachidonic acid (20:4n-6); AdA, docosatetraenoic acid (trivial name adrenic acid; 22:4n-6); OA, omega-6 docosapentaenoic acid (trivial name osbond acid; 22:5n-6); total n6, total levels of omega-6 fatty acids; ALA, α-linolenic acid (18:3n-3); EPA, eicosapentaenoic acid (20:5n-3); DPA omega-3 docosapentaenoic acid (22:5n-3); DHA docosahexaenoic acid (22:6n-3); total n3, total levels of omega-3 fatty acids; n6:n3, ratio of total levels of omega-6 to total levels of omega-3 fatty acids.
Adjusted for gender; ethnic group; highest parental social class; maternal education; birth weight; family adversity index, body mass index at age 7 years; energy intake at age 7 years.