Table 3.
ROC curve analysis for ADC, D, D*, and Kapp values in discriminating lung cancers with high and low Ki-67 expression
| Parameters | Cut-off value | Sensitivity (%) | Specificity (%) | AUROC (95% CI) | Youden index | P |
|---|---|---|---|---|---|---|
| ADC (×10-3mm2/s) | 1.42 | 45.1 | 93.5 | 0.68 (0.53 -0.84) | 0.39 | 0.029 |
| D (×10-3mm2/s) | 0.98 | 90.2 | 77.4 | 0.85 (0.73 - 0.97) | 0.67 | 0.000 |
| D*(×10-3mm2/s) | 13.1 | 85.2 | 45.2 | 0.65 (0.49 -0.81 | 0.31 | 0.073 |
| Kapp | 0.78 | 51.6 | 85 | 0.69 (0.55 - 0.83) | 0.37 | 0.023 |
ROC: receiver operating characteristic; ADC: apparent diffusion coefficient; D: true diffusion coefficient, D* value: the perfusion-related pseudodiffusion coefficient; f: perfusion fraction; Kapp: diffusion kurtosis; Dapp: diffusivity; AUROC: Area under ROC curve; CI: confidence interval.