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. 2021 Jan 1;11(2):540–554. doi: 10.7150/thno.49517

Figure 1.

Figure 1

Combination of anti-CD40 agonistic antibody (αCD40) with focused ultrasound (FUS) induced boiling histotripsy (HT) activates the tumor microenvironment to enhance the efficacy of immune checkpoint inhibitors in poorly immunogenic tumors.