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Knockout of PGC-1α with siRNA aggravates oxidative stress and apoptosis following SAH. (A) Representative western blot images; (B) Quantitative analyses of MC1R, p-AMPK, SIRT1, PGC-1α, UCP2, GPx, SOD, CC-3, Bcl-2, Bax. Data were shown as means ± SD, and were compared using 1-way ANOVA followed by the Tukey post hoc test. *p < 0.05 vs. sham, &p < 0.05 vs. SAH + vehicle, #p < 0.05 vs. SAH + BMS-470539.
