Figure 5.

Quantification of the clustering coefficients for the retinal vasculature in P12 mice under normoxia and OIR conditions. (A) Representative 3-D scatter plots of the clustering coefficients demonstrate all the branching nodes and terminal nodes traced. ~90% of the nodes have a cluster coefficient of zero (grey nodes). ~10% of the nodes have clustering coefficients ranging from 0.05 to 1 in both normoxia and OIR mice. (B) The histogram of clustering coefficients and degree of nodes demonstrates that the majority of the nodes have three connecting neighbors with a paucity of neighbor connection in a normoxia mouse. (C) Despite the significant reduction of the global connectivity and number of nodes, the OIR mouse demonstrated the same trend in local patterns as the normoxia mouse, with the majority of the nodes sharing three connecting neighbors with a paucity of neighboring connections.