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. 2021 Jan 1;12(2):611–621. doi: 10.7150/jca.52234

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Knockdown circular PVT1 suppressed cell viability, migration and invasion. (A and C) qPCR analysis revealed that circPVT1 level in si-circPVT1-1 treated groups were weaker than that in si-NC treated groups in SKOV3 and A2780 cells. (B and D) CCK-8 analysis revealed that circular PVT1 knockdown suppressed SKOV3 and A2780 cell viability. (E-G) Transwell assay showed circular PVT1 knockdown suppressed SKOV3 and A2780 cell invasion. (H-J) Transwell assay showed circular PVT1 knockdown suppressed SKOV3 and A2780 cell migration.