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. 2021 Jan 1;12(2):530–538. doi: 10.7150/jca.51136

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DESC1 is a key downstream target of LOXL1-AS1. (A, D) Screening of differentially expressed genes by RNA-seq (≥ 2-fold change) after knockdown of LOXL1-AS1 in KYSE30 cells through volcano plot (A) and bar chart (D). (B) Hierarchical clustering of altered differential genes after inhibition of LOXL1-AS1 in KYSE30 cells. (C) The relative expression of DESC1 in human esophageal carcinoma (ESCA) compared with normal esophageal tissues in GEPIA database. (E) The expression of DESC1 was measured by qRT-PCR after silencing of LOXL1-AS1 in KYSE30 cells. *P <0.5, ***P < 0.001.