Table 2.
Univariate Cox regression analysis for PFS
| HR | 95% CI | P-value | |
|---|---|---|---|
| Age (<65 versus ≥65 years) | 0.83 | 0.44-1.59 | .5778 |
| Gender (Male versus female) | 0.92 | 0.49-1.73 | .7862 |
| Response to first-line treatment (SD/PD versus CR/PR) | 1.96 | 1.02-3.79 | .0440 |
| Previous Surgery (Yes versus no) | 0.46 | 0.24-0.90 | .0223 |
| Primary tumor location (right versus left) | 2.04 | 1.02-4.07 | .0428 |
| Number of organ metastasis (≥2 versus 1) | 2.19 | 1.09-4.39 | .0278 |
| CEA (<5 ng/mL versus ≥5 ng/mL) | 0.41 | 0.21-0.80 | .0088 |
| RAS/RAF mutated (Yes versus no) | 2.36 | 1.17-4.74 | .0161 |
| Peritoneal seeding (Yes versus no) | 0.75 | 0.38-1.49 | .4075 |
HR, hazard ratio; CI, confidence interval; CR, complete response; PR, partial response; SD, stable disease; PD, progressive disease; CEA, carcinoembryonic antigen.