Fig. 6.

The miR-34a antagomir increased the levels of its targets synaptotagmin-1 and improved spine morphology (n = 3–5). (A) Representative photomicrograph of synaptotagmin-1 and a summary of data obtained from the western blots. (B) Representative photomicrograph and summary data for Golgi staining. ^#p < 0.05 compared with the Control-vehicle group. *p < 0.05 compared with the Chronic stress-vehicle group. Two-way ANOVA results of (A) Stress F(1,16) = 14.38, p < 0.01; Treatment F(1,16) = 8.47, p < 0.05; Interaction F(1,16) = 1.38, p > 0.05; (B) Stress F(1,8) = 5.80, p < 0.05; Treatment F(1,8) = 8.35, p < 0.05; Interaction F(1,8) = 9.80, p < 0.05.