Table 2.
|
CR (n = 20)
|
PR + NR (n = 10)
|
P
value
|
Demographics | |||
Age at AMAT [yr (IQR)] | 28 (24-32) | 26 (25-47) | 0.66 |
Sex (M) | 11 | 4 | 0.70 |
Duration of disease [yr (IQR)] | 4 (1-8) | 2 (1-4) | 0.45 |
Time between diagnosis and stricture [yr (IQR)] | 3 (0-6) | 1.5 (0-3) | 0.54 |
Stricture outcome | |||
Single stricture, n (%) | 19 (95) | 7 (70) | 0.10 |
Multiple strictures, n (%) | 1 (5) | 3 (30) | |
Clinical outcome | |||
Clinical response, n (%) | 16 (80) | 5 (50) | 0.12 |
No clinical response, n (%) | 4 (20) | 5 (50) | |
Pathology | |||
CRP [mg/L (IQR)] | 4 (3-10) | 6 (4-8) | 0.71 |
ESR [mm/h (IQR)] | 5 (2-9) | 6 (4-11) | 0.86 |
Area of involvement | |||
ICV, n (%) | 8 (40) | 4 (40) | |
TI, n (%) | 12 (60) | 5 (50) | |
ICV + TI, n (%) | 0 (0) | 1 (10) | |
Duration of AMAT for stricture outcome | |||
≤ 12 mo, n (%) | 10 (50) | 3 (30) | 0.44 |
> 12 mo, n (%) | 10 (50) | 7 (70) |
Clinical outcomes: (1) Clinical response with complete resolution (CR): n = 16 (7, asymptomatic; 9, improved); (2) clinical response with partial resolution (PR) + no resolution (NR): n = 5 (1, asymptomatic; 4, improved); (3) no clinical response with CR: n = 4 (4, no change); and (4) no clinical response with PR + NR: n = 5 (4, no change; 1, worsened). CR: Complete resolution; PR: Partial resolution; NR: No resolution; AMAT: Anti-mycobacterial antibiotic therapy; IQR: Interquartile range; M: Male; CRP: C-reactive protein; ESR: Erythrocyte sedimentation rate; ICV: Ileocecal valve; TI: Terminal ileum.