Table 7.
Confounder model
| |||
Variable
|
Estimate
|
95%CI
|
P
value
|
Female sex | 0.62 | 0.50-0.65 | 0.159 |
Age at ultrasound (in years) | 0.99 | 0.98-1.03 | 0.637 |
BMI at ultrasound (in years) | 1.28 | 0.71-1.85 | < 0.001c |
Diabetes mellitus | 2.14 | 0.95-4.79 | 0.441 |
Hypertension | 2.89 | 2.51-4.10 | 0.037a |
Dyslipidemia | 1.46 | 0.98-2.84 | 0.695 |
Current smoking | 1.77 | 1.26-2.40 | 0.525 |
Steroid use | 0.88 | 0.20-1.54 | 0.652 |
Parameters included in model with age and BMI | |||
Elevated SCCAI | 1.58 | 1.42-1.74 | 0.145 |
Inflammation in colonoscopy | 3.60 | 2.69-4.50 | 0.005b |
Inflammation in bowel ultrasound | 2.31 | 2.16-2.47 | 0.162 |
Elevated CRP concentration | 0.99 | 0.83-1.14 | 0.959 |
Elevated white blood cell count | 1.01 | 0.85-1.17 | 0.782 |
Elevated fecal calprotectin concentration | 1.06 | 0.90-1.22 | 0.923 |
History of bowel resection(s) | 1.66 | 1.50-1.82 | 0.332 |
Biologic treatment | 0.69 | 0.53-0.85 | 0.167 |
Adalimumab treatment | 0.74 | 0.58-0.90 | 0.426 |
Infliximab treatment | 0.77 | 0.62-0.93 | 0.484 |
Vedolizumab treatment | 1.14 | 0.98-1.30 | 0.739 |
Ustekinumab treatment | 0.19 | 0.03-0.35 | 0.407 |
Golimumab treatment | 1.14 | 0.98-1.30 | 0.892 |
Azathioprine therapy | 1.19 | 1.03-1.35 | 0.597 |
Methotrexate treatment | 1.50 | 1.34-1.66 | 0.734 |
6-Mercaptopurine treatment | 0.94 | 0.79-1.10 | 0.947 |
Sulfasalazine treatment | 1.43 | 1.27-1.58 | 0.491 |
Mesalazine treatment | 0.88 | -0.25-2.00 | 0.635 |
P < 0.05.
P < 0.01.
P < 0.001. BMI: Body mass index; CRP: C-reactive protein; SCCAI: Simple Clinical Colitis Activity Index; CI: Confidence interval.