Table 3.
Regression analyses of prenatal discrimination (EDS) as a continuous predictor of postnatal symptoms stratified by higher or lower than average TNF-α promoter or FOXP3 TSDR methylation status.
|
TNF-α methylation | |||||
|---|---|---|---|---|---|
| Outcome | B | SE B | β | p-value | |
| HIGH methylation | preEDS postGAD | .531 | .219 | .324 | .019 |
| preEDS postIDAS | .103 | .026 | .489 | <.0001 | |
| preEDS postEPDS | .434 | .171 | .338 | .014 | |
| LOW methylation | preEDS postGAD | .200 | .199 | .108 | .317 |
| preEDS postIDAS | .024 | .018 | .145 | .181 | |
| preEDS postEPDS | .099 | .175 | .061 | .573 | |
| FOXP3 | |||||
| Outcome | B | SE B | β | p-value | |
| HIGH methylation | preEDS postGAD | .489 | .114 | .440 | <.0001 |
| preEDS postIDAS | .091 | .015 | .568 | <.0001 | |
| preEDS postEPDS | .437 | .087 | .502 | <.0001 | |
| LOW methylation | preEDS postGAD | .404 | .340 | .153 | .240 |
| preEDS postIDAS | .037 | .026 | .180 | .166 | |
| preEDS postEPDS | .322 | .316 | .131 | .313 | |