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. 2020 Oct 31;13:100266. doi: 10.1016/j.ynstr.2020.100266

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© 2020 The Authors. Published by Elsevier Inc.

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

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Fig. 2 — Effects of chemogenetic inhibition of the PVT-NAcSh projection on social approach-avoidance. Effects of chemogenetic inhibition of the PVT-NAcSh projection on SAA on Day 14 (A–B) and Day 18 (C–D) in rats treated with systemic injections of clozapine (Clz) to activate hM4Di (left side) or local administrations of CNO in the NAcSh (right side). Data are means ± SEM. *p < 0.05. Group sizes are n = 6 to 12. (NS + mCherry + Clz, n = 6; NS + hM4Di + Sal, n = 7; NS + hM4Di + Clz, n = 6; LR + mCherry + Clz, n = 8; LR + hM4Di + Sal, n = 11; LR + hM4Di + Clz, n = 10; HR + mCherry + Clz, n = 7; HR + hM4Di + Sal, n = 9; HR + hM4Di + Clz, n = 9; LR + hM4Di + Sal in NAcSh, n = 12; LR + hM4Di + CNO in NAcSh, n = 12; HR + hM4Di + Sal in NAcSh, n = 12; HR + hM4Di + CNO in NAcSh, n = 11.)