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. 2020 Oct 31;13:100266. doi: 10.1016/j.ynstr.2020.100266

Fig. 4.

Fig. 4

Effects of chemogenetic inhibition of the PVT-NAcSh projection on contextual fear. Effects of chemogenetic inhibition of the PVT-NAcSh projection on freezing to the shock context in rats treated with systemic injections of clozapine (Clz) to activate hM4Di (A) or local administrations of CNO in the NAcSh (B). Data are means ± SEM. Group sizes are n = 6 to 11. (NS + mCherry + Clz, n = 6; NS + hM4Di + Sal, n = 6; NS + hM4Di + Clz, n = 7; LR + mCherry + Clz, n = 8; LR + hM4Di + Sal, n = 10; LR + hM4Di + Clz, n = 11; HR + mCherry + Clz, n = 7; HR + hM4Di + Sal, n = 9; HR + hM4Di + Clz, n = 9; LR + hM4Di + Sal in NAcSh, n = 11; LR + hM4Di + CNO in NAcSh, n = 11; HR + hM4Di + Sal in NAcSh, n = 10; HR + hM4Di + CNO in NAcSh, n = 10.)