Fig. 5.

U50,488 altered GABAergic synaptic transmission onto LHb neurons. A. U50,488 decreased the mean amplitude of mIPSCs and decreased the cumulative probability of mIPSC amplitude. B. Representative mIPSC traces at baseline (black) and following U50,488 treatment (red). Out of 14 recorded cells from A., U50,488 treatment decreased the average of mIPSC frequency as well as the cumulative probability of inter-event intervals of mIPSCs in 10 recorded cells. C. Representative mIPSC traces at baseline (black) and following U50,488 treatment (red). Out of 14 recorded cell in A., U50,488 treatment increased the average frequency and the cumulative probability of inter-event intervals of mIPSCs in 4 recorded cells (n = 4/4). *p < 0.05, **p < 0.01, ***p < 0.0001. (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)