Table 1.

PERMANOVA of the effects of variables on beta-diversity determined using adonis2.

Variables		Stool Samples		Bray-Curtis		Unweighted Unifrac			Weighted Unifrac
		R2			P	R2	P		R2		P
Species-level differences	Sex	All	0.011		0.386	0.014		0.171		0.015		0.157
	Social manipulation	all	0.015		0.131	0.01		0.541		0.011		0.454
	Pre- vs. Post-	all	0.012		0.339	0.008		0.758		0.013		0.262
	Social manipulation	pre-only	0.025		0.270	0.018		0.625		0.027		0.254
	Social manipulation	post-only	0.040		0.023*	0.015		0.820		0.049		0.034*
	Pre- vs. Post-	isolation	0.023		0.385	0.014		0.893		0.035		0.127
	Pre- vs. Post-	cohoused	0.035		0.033*	0.016		0.775		0.044		0.041*
	Pre-all vs Isolation-post vs Cohoused-post	all	0.031		0.064	0.017		0.826		0.039		0.024*
Family-level differences	Sex	all all all pre-only post-only isolation cohoused all	0.014 0.01 0.008 0.031 0.032 0.033 0.023 0.023		0.257 0.449 0.620 0.200 0.190 0.159 0.333 0.330	0.017 0.01 0.008 0.011 0.006 0.010 0.006 0.019		0.144 0.652 0.648 0.834 0.937 0.821 0.945 0.584		0.018 0.008 0.011 0.042 0.045 0.030 0.067 0.035		0.137 0.543 0.401 0.121 0.112 0.238 0.031* 0.128
	Social manipulation
	Pre- vs. Post-
	Social manipulation
	Social manipulation
	Pre- vs. Post-
	Pre- vs. Post-
	Pre-all vs Isolation-post vs
	Cohoused-post

* Significant at p < 0.05.