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. 2020 Dec 3;21(2):116. doi: 10.3892/etm.2020.9548

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Copyright: © Fu et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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miR-451a promotes cSCC cell apoptosis. (A) Apoptotic A431 and SCC-12 cells transfected with miR-451a mimics or mimic controls were determined by flow cytometric analysis. (B) Hoechst 33258 staining of A431 and SCC-12 cells transfected with the miR-451a mimic or mimic control. Scale bar, 50 µm. (C) Bax and Bcl-2 concentrations in A431 and SCC-12 cells transfected with the miR-451a mimic or mimic control were analyzed using ELISAs. The data are presented as the mean ± SD. One-way ANOVA and Tukey's multiple comparison tests were used to determine statistical significances. ^*P<0.05. miR, microRNA; cSCC, cutaneous squamous cell carcinoma; PI, propidium iodide.