Table III.
Multivariate logistic regression analyses of PNI as a predictor for AKI in the test cohort.
| A, All study participants (n=6,444) | ||||
|---|---|---|---|---|
| PNI on admission | Unadjusted OR | Adjusted ORa | 95% CI | P-value |
| Quartile 1 (>61.0) | 1.0 (ref.) | 1.0 (ref.) | ||
| Quartile 2 (42.6-61.0) | 1.652 | 1.414 | 1.170-1.708 | <0.001 |
| Quartile 3 (34.1-42.5) | 1.799 | 1.447 | 1.195-1.753 | <0.001 |
| Quartile 4 (<34.0) | 1.897 | 1.765 | 1.457-2.137 | <0.001 |
| B, Patients without preexisting CKD (n=4,990) | ||||
| PNI on admission | Unadjusted OR | Adjusted ORa | 95% CI | P-value |
| Quartile 1 (>53.5) | 1.0 (ref.) | 1.0 (ref.) | ||
| Quartile 2 (43.1-53.5) | 2.229 | 1.817 | 1.484-2.226 | <0.001 |
| Quartile 3 (34.0-43.0) | 2.398 | 1.852 | 1.484-2.226 | <0.001 |
| Quartile 4 (<34.0) | 3.084 | 2.262 | 1.820-2.811 | <0.001 |
| C, Patients with preexisting CKD (n=1,454) | ||||
| PNI on admission | Unadjusted OR | Adjusted ORa | 95% CI | P-value |
| Quartile 1 (>55.0) | 1.0 (ref.) | 1.0 (ref.) | ||
| Quartile 2 (41.6-55.0) | 2.394 | 2.215 | 1.358-3.613 | 0.001 |
| Quartile 3 (33.0-41.5) | 2.457 | 2.389 | 1.469-3.883 | <0.001 |
| Quartile 4 (<33.0) | 2.492 | 2.506 | 1.528-4.110 | <0.001 |
aAdjusted for age, sex, BMI, hypertension, diabetes, eGFR, hemoglobin, leucocyte, mean arterial pressure, triglyceride, total cholesterol, potassium, sodium and APSIII points. OR, odds ratio; 95% CI, 95% confidence interval; CKD, chronic kidney disease; eGFR, estimate glomerular filtration rate; PNI, prognostic nutritional index; AKI, acute kidney injury.