Table IV.
Multivariate Cox regression analyses: Predictors of hospital mortality and 2-year mortality in test and validation sets.
| A, in-hospital mortality | ||||
|---|---|---|---|---|
| Test set | Validation set | |||
| Parameter | Adjusted HR (95% CI) | P-value | Adjusted HR (95% CI) | P-value |
| APACHEII score | - | - | 1.121 (1.040-1.208) | 0.003 |
| PNI | 0.978 (0.975-0.981) | <0.001 | 0.882 (0.845-0.921) | <0.001 |
| MAP, mmHg | 0.977 (0.964-0.989) | <0.001 | 0.986 (0.974-0.999) | 0.034 |
| APSIII score | 1.003 (1.001-1.006) | 0.016 | - | - |
| eGFR, ml/min | 0.994 (0.992-0.996) | <0.001 | 0.982 (0.955-1.010) | 0.210 |
| B, 2-year mortality | ||||
| Test set | Validation set | |||
| Parameter | Adjusted HR (95% CI) | P-value | Adjusted HR (95% CI) | P-value |
| APACHEII score | - | - | 1.145 (1.080-1.214) | <0.001 |
| PNI | 0.984 (0.983-0.986) | <0.001 | 0.906 (0.877-0.936) | <0.001 |
| MAP, mmHg | 0.974 (0.965-0.982) | <0.001 | 0.983 (0.973-0.993) | 0.001 |
| APSIII score | 1.021 (1.017-1.024) | <0.001 | - | - |
| eGFR, ml/min | 0.997 (0.995-0.999) | 0.006 | 1.001 (0.988-1.014) | 0.855 |
| Age, years | 1.014 (1.012-1.016) | <0.001 | 1.002 (0.980-1.025) | 0.857 |
| Preexisting CKD | 1.223 (1.098-1.363) | <0.001 | 1.008 (0.548-1.856) | 0.979 |
| Hypertension | 1.255 (1.155-1.365) | <0.001 | 1.166 (0.762-1.783) | 0.480 |
Multivariate model for in-hospital mortality and 2-year mortality are adjusted for age, sex, BMI, hypertension, diabetes, CKD, eGFR, hemoglobin, leucocyte, mean arterial pressure, triglyceride, total cholesterol, serum potassium and serum sodium and APACHEII or APSIII points. HR, hazard ratio; CI, confidence interval; APACHEII, acute physiology and chronic health evaluation II; PNI, prognostic nutritional index; MAP, mean arterial pressure; APSIII, acute physiology score III; eGFR, estimate glomerular filtration rate; CKD, chronic kidney disease.