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. 2020 Nov 9;7(24):2001657. doi: 10.1002/advs.202001657

Figure 5.

Figure 5

The synergy of CXCR4 and VEGFa genes codelivered into EPCs. A) Schematic illustration of the synergistic reendothelialization of combination therapy with CXCR4 and VEGFa genes transfected in EPCs. B) The mRNA expressions of related molecular targets in EPCs receiving CXCR4 and VEGFa codelivery quantified by qPCR analysis. Data are shown as mean ± SD, n = 3. *P < 0.05, **P < 0.01. C) The protein expressions of related molecular targets in EPCs receiving CXCR4 and VEGFa codelivery analyzed by Western blot. D) Density quantification of protein expression of related molecular targets in EPCs receiving CXCR4 and VEGFa codelivery. Abbreviations: PDGF, platelet derived growth factor; FGF, fibroblast growth factor; eNOS, endothelial nitric oxide synthase; AKT, protein kinase B; GAPDH, glyceraldehyde‐3‐phosphate dehydrogenase.