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. 2020 Nov 9;11:570893. doi: 10.3389/fphar.2020.570893

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Copyright © 2020 Qiu, Huang, Liu, Huang, Li, Cui, Luo and Luo

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-COV-2) is an enveloped RNA virus, comprising RNA and four major structural proteins [the nucleocapsid (N) protein, membrane (M) glycoprotein, envelope (E) protein, and spike (S) glycoprotein]. The pathogenic mechanism includes the four steps: attachment and entry, replication and transcription, assembly, and release. The virus mainly invades the host through the respiratory tract and directly or indirectly causes systemic multiple organ damage by identifying specific receptors on the host cell membrane.